Molecular Diagnostics 320-ERS-1MODL

Substantive content:
Molecular diagnostics in a scientific sense means the identification of any organism (from viruses to mammals) and the detection of its genetic or genomic variants. The main goal from a medical perspective is to precisely detect different pathogens, genetic disorders, and tumor DNA/ RNA for diagnosis, prognosis, and monitoring response to therapy. As a connection of laboratory medicine, genetic/genomic knowledge, and technology Molecular diagnostics provides the accurate diagnosis.
During the course, students will get an overview of the field of molecular diagnostics and different, modern molecular diagnostic methods. Students will also learn about the role of GWAS (genome-wide association studies), candidate gene approach, and others in surveys of complex diseases, pharmacogenetics, and nutrigenetics. During the laboratory work students will perform simple molecular diagnostic tests using PCR and DNA sequencing approaches. Students will also get familiar with the possibilities provided by the GTR (Genetic Testing Registry) online platform that belongs to NCBI.